Glycosylated asterisks are among the most potent low valency inducers of Concanavalin A aggregation.

نویسندگان

  • Mazen Sleiman
  • Annabelle Varrot
  • Jean-Manuel Raimundo
  • Marc Gingras
  • Peter G Goekjian
چکیده

A new class of sulfurated, semi-rigid, radial and low-valent glycosylated asterisk ligands with potential dual function as ligand and probe has some of the highest inhibition potencies of Con A-induced hemagglutination, by using a cross-linking mechanism of Con A which amplifies the enhancement to near nanomolar concentrations with the alpha-d-mannose asterisk.

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عنوان ژورنال:
  • Chemical communications

دوره 48  شماره 

صفحات  -

تاریخ انتشار 2008